The Clinical Laboratories support NASA's medical operations in ensuring crew health and safety for the Space Shuttle and International Space Station.
Wyle personnel support the Clinical Laboratory by performing medical clinical analysis, 
including bio-chemistry, immunology, hematology, and urinalysis for the astronaut corps, for participants in the Longitudinal Study of Astronaut Health, and for test subjects. Wyle employees collect pre- and post-flight samples from the Shuttle and International Space Station crews and provide analysis or support of ground-based studies and in-flight experiments. The Laboratory maintains an active database that includes all analyses since the human space program began, and maintains a repository of biological specimens from all astronauts. In addition, the Clinical Laboratory performs tests for analytes to determine metabolic function and bone status, and is responsible for analyzing urine samples.
Wyle employees performed initial testing of the handheld portable clinical blood analyzer. The Clinical Laboratory has an exceptional record in maintaining College of American Pathologist (CAP) certification, which requires a biannual external inspection. The laboratory is responsible for patient records, specialized data reports, and maintenance of the Clinical Laboratory Information Management System.