Wyle's employees contribute to a wide range of important projects including the International Space Station, the Crew Medical Support Office of the European Space Agency at the European Astronaut Center (Cologne), the Flight Medicine Center at the Deutsches Zentrum für Luft- und Raumfahrt (DLR / German Center for Air and Space Travel - Cologne) as well as the Women International Space Simulation for Exploration Bed Rest research study conducted at the Institut de Medecine et de Physiologie Spatiales (MEDES / Institute for Space Medicine and Physiology) in Toulouse, France.